关键词: font-family:宋体, ">获得性免疫缺陷综合征；肝功能；影响因素；font-family:", ">Logisticfont-family:宋体, ">回归分析

Abstract:

Objective：To investigate the correlation between alanine aminotransferase （ALT）， aspartate aminotransferase （AST） and peripherally hematic factors in AIDS patients in order to provide guidance for better treatment of liver damage. Methods：2 968 AIDS patients from database of a pilot project named Traditional Chinese Medicine Treatment for HIV in Yunnan， including 816 patients with abnormal ALT and 777 with abnormal AST， were enrolled in this study.General clinical information and measures of laboratory test were collected. Logistic regression analysis was performed to explore the factors related to liver damage. Results： The liver damage was significantly correlated with alterations of Hb， PLT and CD4+T lymphocytes. Logistic regression analysis showed that the levels of ALT and AST were positively correlated with Hb（P<0.05）， whereas negatively correlated with PLT and CD4+T lymphocytes. Conclusion：In AIDS patients with impaired liver function in Yunnan Province， the levels of ALT and AST are closely related to the levels of Hb， PLT， and CD4+T lymphocytes.

Key words:

"> AIDS">； liver function">； affective factors">； logistic regression analysis